The partnership between BMD and pounds try stronger than between Bmi and BMD
step three.3. Risk Things
Compared with men with BMI? 25 kg/m 2 , the age-adjusted risk of osteoporosis was over four-fold higher in those with BMI < 25 (odds ratio (OR) 4.4 (1.51, ) in age-adjusted model (Table 3). The association between BMI and osteopenia was similar among overweight/obese and normal weight men, although not statistically significant (Table 3).
Each other Body mass index and you may pounds had been coordinated that have BMD, and you will BMC symptoms as well as the strongest Pearson’s relationship coefficients had been discovered between weight and BMC overall cool and you may trochanter nations and you can the fresh weakest of them was basically ranging from Bmi and you may femoral shoulder BMC. The new correlations between age and you will BMD and you will BMC indications have been bad (Desk 4).
The age-adjusted proportion off BMD and you will BMC type explained because of the Body mass index and lbs was found from inside the Desk 5. Lbs tended to inform you better variations in BMD and you can BMC delivery after all the brand new read skeletal internet sites as compared to Bmi. This is mirrored of the steeper hill (?) of the respective linear regression contours. The most effective difference between BMD and you may BMC delivery looked in the trochanter BMC with lumbar BMC for weight. Weight is an important predictor regarding BMD and you can BMC version during the more mature Iranian men.
4. Conversation
In this study, both BMI and weight were associated with BMD, and obesity significantly decreased the risk for osteoporosis in men. These results are consistent with most previous studies, particularly in postmenopausal women, which indicated that lower BMI and weight were associated with lower BMD. Prospective studies found that the early postmenopausal women who have low BMI lose more bones compared to those with higher BMI tertiles [4, 8]. In other cross-sectional studies, however, thinness is related to both osteoporosis and increased fracture risk [10, 11]. Iqbal et al. found that low BMI is a good indicator for referral of women less than 60 years old for measurements of BMD. Similar studies also reported a consistent finding that lower BMI was associated with lower BMD [5, 6, 28]. In a study similar to ours, those with lower BMI were at higher risk of low BMD . The Studies of National Osteoporosis Foundation and others suggested that low BMI looking for a sugar daddy to send me money Minneapolis Minnesota should be included in the risk assessment tools for evaluation of osteoporosis and osteoporotic fracture risk [29–31]. We found that men with BMI < 25 had 4.4 (95% CI 1.5, 12.8) times higher age-adjusted risk of osteoporosis than men with BMI ? 25. In contrast, Steinschneider et al. in a cross-sectional study reported that the correlation between BMD at the femoral neck and BMI was highly positive among postmenopausal women. A hospital-based study conducted in elderly men reported that overweight and obese men were more likely to have osteoporosis and osteopenia . The possible explanation for the discrepancies between these results might be related to populations, research designs, sampling methods, and methodological differences.
The fresh mechanisms for which adipose tissue exerts positive effects into BMD status are not totally obvious. Brand new putative process relevance of fatty tissue for skeletal integrity probably resides in the latest role of several adipokines into the limbs remodeling thanks to affect both formation and you will resorption. Has just, limbs has been sensed an hormonal body organ impacting weight control and you can glucose homoeostasis from tips off limbs-derived situations for example osteocalcin and osteopontin [23, 34–36]. The putative crosstalk anywhere between fat additionally the skeleton comprises an effective homoeostatic views program in which adipokines and you will particles secreted by the osteoblasts and you will osteoclasts represent the link out-of an active bone-adipose axis [34–36]. Obesity is also of the BMD because of the conversion of androgen to the hormone estrogen , which enhances limbs bulk both in folk [38, 39] and you will retains fit plasma levels of insulin and you may managing things in addition to insulin-such as for instance progress grounds-step one, leptin, and adiponectin . Likewise, obesity will bring padding toward stylish in the eventuality of good slide . But not, the components wherein many of these incidents exist remain unclear.
